The “Phayao IT Campus” of Naresuan University was established to extend educational opportunities and equality to people in the regional areas of the country. The proposal was approved by the cabinet on 20 June 1995. The cabinet resolution, dated 8 October 1996, later indicated that the campus would be called “Phayao IT Campus”. During the first academic years, the students of the IT Campus temporarily took classes at Phayao Phittayakom School – a provincial grade school. Instructions at MIS, then a section in the Liberal Arts Academic Cluster, began in 1995 on the tri-semester basis. The first degree program available was the Bachelor of Business Administration, soon followed by a bachelor degree program in accounting. The campus would soon move to its current location in Mae Ka, Muang District, Phayao Province, which is approximately 17-18 kilometers from the downtown area. In 1999, the section began to enroll students into the regular bi-semester programs in business management and accounting, along with its remaining tri-semester programs. MIS would remain with the Liberal Arts Academic Cluster until March 28, 2004 when the Management and Information Technology Academic Cluster was inaugurated. On December 1, 2004, the Academic School of Management and Information Technology was established with the 4 initial academic sections under its roof: business management, accounting, mass communication and tourism.
As of today, the School of Management and Information Technology gained the status of an academic faculty under the Phayao University Act. Successive restructuring of the school finally ended with its 7 academic divisions: business management, accounting, mass communication, hotel and tourism management, economics, information technology for communication, and finance and banking.