The “Phayao IT Campus” of Naresuan University was established to extend education opportunities and equality to people in the regional areas of the country. The proposal for the establishment of the campus was approved by the cabinet on 20 June 1995. The cabinet resolution, dated 8 October 1996, later indicated that the campus would be called “Phayao IT Campus”. It was a satellite campus of Naresuan University, located in Mae Ka Sub-District, Muang District, Phayao Province – a land-grant location sponsored by the Ministry of Interior and the Provincial Administration of Phayao. The IT Campus began to enroll students in the fields related to the sciences and technology in the year 2000, providing 3 initial programs in horticulture, fishery and agro-industry. The initial curriculums were designed and administered by the Office of Academic Affairs at the IT Campus, in collaboration with the Faculty of Agriculture, Natural Resources and Environment at Naresuan University’s flagship campus.
On 22 June 2001, Naresuan University – Phayao restructured its divisions into 3 academic clusters: the Information Technology, Liberal Arts, and Science and Technology. The operational responsibilities were distributed according to the programs of study under the charge of each cluster. The Science and Technology Academic Cluster was responsible for the administration of 3 programs: horticulture, fishery and agro-industry. Students majoring in agro-industry were required to continue their third and fourth year of study at the flagship campus of Naresuan University in Phitsanulok. From 2002, the Science and Technology Cluster began to enroll students into the chemistry and biology programs, which were added later to the division, with Dr. Santhiwat Phitakphol acting as the first chairperson of the cluster.
The Science and Technology Cluster at the IT Campus was committed to upgrading the people’s quality of life, especially by integrating knowledge, innovations in sciences and technology with the local wisdoms in accordance to the local climatic, economic and social conditions of the upper-northern region. In addition to helping to develop the economy of the upper-northern region, this could help reduce the financial burden of the students in the region who wish to continue their higher education in Agriculture and Natural Resources without having to attend universities in other regions. On 28 June, 2004, Naresuan University – Phayao once again restructured its administrative system and transferred the horticulture, fishery and agro-industry programs to the newly founded Academic School of Agriculture, Natural Resources and Environment. The Science and Technology Cluster, now the Academic School of Science and Technology, later inaugurated more programs in micro-biology, physics, mathematics, material sciences and statistics in addition to the remaining 2 programs in chemistry and biology. To date, the School of Science and Technology provides 6 undergraduate programs and a master program in biotechnology.